分子量:81 kDa纯度:>95% as determined by SDS-PAGE.内毒素:Less than 1.0 EU per μg of the Human DLL4, Fc Tag by the LAL method.Buffer:50 mM tris, 100 mM glycine, pH7.5生物活性:产品特性:Human DLL4, Fc Tag is fused with a human IgG1 Fc tag at the C-terminus, and has a calculated MW of 81 kDa. The predicted N-terminus is Ser 27. The reducing (R) protein migrates as 100-110 kDa in SDS-PAGE  due to glycosylation.产品背景:Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4). DLL4 contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 plays a role in the Notch signaling pathway. DLL4 activates Notch-1 and Notch-4. 

SDS-PAGE