产品名称

Varenicline dihydrochloride - Chantix | Champix

产品货号

Axon 1384 CAS [866823-63-4] MF C13H13N3.HClMW 284.18 Purity: 99% Soluble in water Description Selective α4β2 nicotinic acetylcholine receptor partial agonist; Smoking cessation drug. Available also another drug form, Varenicline tartrate (Axon 2074). References Certificates Categories Extra info DE Jorenby et al. Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial. JAMA 2006, 296 (1), 56–63. RS Obach et al. Metabolism and disposition of varenicline, a selective alpha4beta2 acetylcholine receptor partial agonist, in vivo and in vitro. Drug Metab Dispos 2006, 34, 121-30. Mihalak K.B. et al. Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors. Mol Pharmacol. 2006 Sep;70(3):801-805. Certificate of Analysis Material Safety Data Sheet CNS Pain & Inflammation nAChR Unclassified Pfizer Licensed Products Nicotinic acetylcholine receptor agonist Chemical name 7,8,9,10-tetrahydro-6,10-methano-6H-pyrazino(2,3-h)(3)benzazepine dihydrochloride Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [249296-44-4] Order Size Unit Price Stock 10 mg €85.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

Varenicline dihydrochloride - Chantix | Champix

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 1384

CAS [866823-63-4]

MF C13H13N3.HCl
MW 284.18

Purity: 99%
Soluble in water

Varenicline dihydrochloride

Description

Selective α4β2 nicotinic acetylcholine receptor partial agonist; Smoking cessation drug. Available also another drug form, Varenicline tartrate (Axon 2074).

DE Jorenby et al. Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial. JAMA 2006, 296 (1), 56–63.

RS Obach et al. Metabolism and disposition of varenicline, a selective alpha4beta2 acetylcholine receptor partial agonist, in vivo and in vitro. Drug Metab Dispos 2006, 34, 121-30.

Mihalak K.B. et al. Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors. Mol Pharmacol. 2006 Sep;70(3):801-805.

CNS Pain & Inflammation nAChR Unclassified Pfizer Licensed Products

Nicotinic acetylcholine receptor agonist

Chemical name

7,8,9,10-tetrahydro-6,10-methano-6H-pyrazino(2,3-h)(3)benzazepine dihydrochloride

Source information

Pfizer compound; Sold for research purposes under agreement from Pfizer Inc.

Parent CAS No.

[249296-44-4]

产品资料