产品名称 SSR 504734
产品货号 Axon 1549 CAS [615571-23-8] MF C20H20ClF3N2O.HClMW 433.29 Purity: 99% Optical purity: optical pure Soluble in water and DMSO Description A potent, selective and orally active GlyT-1 inhibitor, blocked the ex vivo uptake of glycine rapidly, reversibly, and for a long duration; exhibiting activity in animal models of schizophrenia, anxiety and depression References Certificates Categories Extra info G Depoortere et al. Neurochemical, electrophysiological and pharmacological profiles of the selective inhibitor of the glycine transporter-1 SSR504734, a potential new type of antipsychotic. Neuropsychopharmacology 2005, 30, 1963–1985.    K Hashimoto. Glycine Transporter Inhibitors as Therapeutic Agents for Schizophrenia. Recent Pat. CNS Drug Discov. 2006, 1, 43-53.  Certificate of Analysis Material Safety Data Sheet CNS GlyT-1 Unclassified GlyT-1 inhibitor Chemical name 2-chloro-3-(trifluoromethyl)-N-((S)-phenyl((S)-piperidin-2-yl)methyl)benzamide hydrochloride Parent CAS No. [742693-38-5] Order Size Unit Price Stock 2 mg €105.00 In Stock
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SSR 504734

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1549

CAS [615571-23-8]

MF C20H20ClF3N2O.HCl
MW 433.29

  • Purity: 99%
  • Optical purity: optical pure
  • Soluble in water and DMSO

SSR 504734

Description

A potent, selective and orally active GlyT-1 inhibitor, blocked the ex vivo uptake of glycine rapidly, reversibly, and for a long duration; exhibiting activity in animal models of schizophrenia, anxiety and depression
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