产品名称

A-92

产品货号

Axon 2720 CAS [1448693-69-3] MF C19H18N10OMW 402.41 Purity: 99% Soluble in DMSO Description A-92 inhibits the stress response of general control nonderepressible 2 kinase (GCN2 or EIF2AK4) (IC50 value of <0.3 μM). Possible chemotherapeutic drug for the treatment of cancer. KEYWORDS: A-92 | supplier | GCN2 inhibitor | A92 | A 92 | CAS [1448693-69-3] | Unfolded Protein Response (EIF2 Selective) | GCN | Inhibitor | Enzymes | GCN2 | eIF2α | EIF2AK4 | General Control Nonderepressible 2 Kinase | tRNA

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

A-92

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 2720

CAS [1448693-69-3]

MF C19H18N10O
MW 402.41

Purity: 99%
Soluble in DMSO

A-92

Description

A-92 inhibits the stress response of general control nonderepressible 2 kinase (GCN2 or EIF2AK4) (IC50 value of <0.3 μM). Possible chemotherapeutic drug for the treatment of cancer.

KEYWORDS: A-92 | supplier | GCN2 inhibitor | A92 | A 92 | CAS [1448693-69-3] | Unfolded Protein Response (EIF2 Selective) | GCN | Inhibitor | Enzymes | GCN2 | eIF2α | EIF2AK4 | General Control Nonderepressible 2 Kinase | tRNA

J Brazeau et al. Triazolo[4,5-d]pyrimidine Derivatives as Inhibitors of GCN2. ACS Med Chem Lett. 2014 Apr 10; 5(4): 282–283.

Cell Signaling & Oncology EC 2.7.11.1 GCN

Inhibitor of GCN2 (EIF2AK4)

Chemical name

3-(1H-Indazol-6-yl)-N-(1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine

Parent CAS No.

[1448693-69-3]

产品资料