产品名称 A 77-01
产品货号 Axon 1744 CAS [607737-87-1] MF C18H14N4MW 286.33 Purity: 99% Soluble in DMSO Description Potent inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM. A-77-01 is a close analogue of A-83-01 (Axon 1421) and has a very similar biological profile of A-83-01. A-83-01 is found to decompose to A-77-01 under certain circumstances and A-77-01 is likely an active component or metabolite of its prodrug A-83-01. KEYWORDS: A 77-01 | supplier | ALK5 inhibitor | A77-01 | A7701 | CAS [607737-87-1] | TGF-β | TGF-beta | RSTK | Enzyme Linked Receptors | activin-like kinase | metabolite | A-83-01
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产品品牌 axonmedchem
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A 77-01

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1744

CAS [607737-87-1]

MF C18H14N4
MW 286.33

  • Purity: 99%
  • Soluble in DMSO

A 77-01

Description

Potent inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM. A-77-01 is a close analogue of A-83-01 (Axon 1421) and has a very similar biological profile of A-83-01. A-83-01 is found to decompose to A-77-01 under certain circumstances and A-77-01 is likely an active component or metabolite of its prodrug A-83-01.

KEYWORDS: A 77-01 | supplier | ALK5 inhibitor | A77-01 | A7701 | CAS [607737-87-1] | TGF-β | TGF-beta | RSTK | Enzyme Linked Receptors | activin-like kinase | metabolite | A-83-01

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