产品名称

ERB 041 - Prinaberel

产品货号

Axon 1898 CAS [524684-52-4] MF C15H10FNO3MW 271.24 Purity: 99% Soluble in 0.1N NaOH(aq) and DMSO Description Highly selective estrogen receptor β (ERβ) agonist, with IC50 value of 5.4 nM for human ERβ which is >200-fold selective over Erα References Certificates Categories Extra info HA Harris et al. Evaluation of an estrogen receptor-beta agonist in animal models of human disease. Endocrinology 2003, 144(10), 4241-4249. KF Koehler et al. Reflections on the discovery and significance of estrogen receptor beta. Endocr Rev. 2005, 26(3), 465-478. XL Wang et al. ERB-041, a selective ER beta agonist, inhibits iNOS production in LPS-activated peritoneal macrophages of endometriosis via suppression of NF-kappaB activation. Mol. Immunol. 2009, 46(11-12), 2413-2418. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Endocrinology Estrogen (ER) NR3A Pfizer Licensed Products Selective estrogen receptor β (ERβ) agonist Chemical name 2-(3-fluoro-4-hydroxyphenyl)-7-vinylbenzo[d]oxazol-5-ol Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [524684-52-4] Order Size Unit Price Stock 10 mg €95.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

ERB 041 - Prinaberel

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1898

CAS [524684-52-4]

MF C15H10FNO3
MW 271.24

Purity: 99%
Soluble in 0.1N NaOH(aq) and DMSO

ERB 041

Description

Highly selective estrogen receptor β (ERβ) agonist, with IC50 value of 5.4 nM for human ERβ which is >200-fold selective over Erα

HA Harris et al. Evaluation of an estrogen receptor-beta agonist in animal models of human disease. Endocrinology 2003, 144(10), 4241-4249.

KF Koehler et al. Reflections on the discovery and significance of estrogen receptor beta. Endocr Rev. 2005, 26(3), 465-478.

XL Wang et al. ERB-041, a selective ER beta agonist, inhibits iNOS production in LPS-activated peritoneal macrophages of endometriosis via suppression of NF-kappaB activation. Mol. Immunol. 2009, 46(11-12), 2413-2418.

Selective estrogen receptor β (ERβ) agonist

Chemical name

2-(3-fluoro-4-hydroxyphenyl)-7-vinylbenzo[d]oxazol-5-ol

Source information

Pfizer compound; Sold for research purposes under agreement from Pfizer Inc.

Parent CAS No.

[524684-52-4]

产品资料