| 产品名称 | Nexturastat A |
| 产品货号 | Axon 2359 CAS [1403783-31-2] MF C19H23N3O3MW 341.40 Purity: 99% Soluble in DMSO Description Potent HDAC6 inhibitor with >600 fold and >190 fold selectivity over HDAC1 and HDAC8, respectively (IC50 values 5 nM, 3 µM, 1 µM for HDAC6, HDAC1, and HDAC8, respectively). Nexturastat A was found to be capable of increasing acetylated α-tubulin levels and it inhibited the growth of B16 melanoma cells, albeit with lower potency than LBH 589 (Axon 1548). References Certificates Categories Extra info J.A. Bergman et al. Selective histone deacetylase 6 inhibitors bearing substituted urea linkers inhibit melanoma cell growth. J. Med. Chem. 2012, 55, 9891-9899. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Epigenetics DNA-damage Response EC 3.5.1.98 HDAC HDAC6 inhibitor with good selectivity over HDAC1 and HDAC8 Chemical name 4-((1-butyl-3-phenylureido)methyl)-N-hydroxybenzamide Parent CAS No. [1403783-31-2] Order Size Unit Price Stock 5 mg €95.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
Nexturastat AAxon 2359 CAS [1403783-31-2] MF C19H23N3O3
DescriptionPotent HDAC6 inhibitor with >600 fold and >190 fold selectivity over HDAC1 and HDAC8, respectively (IC50 values 5 nM, 3 µM, 1 µM for HDAC6, HDAC1, and HDAC8, respectively). Nexturastat A was found to be capable of increasing acetylated α-tubulin levels and it inhibited the growth of B16 melanoma cells, albeit with lower potency than LBH 589 (Axon 1548).
HDAC6 inhibitor with good selectivity over HDAC1 and HDAC8
Chemical name4-((1-butyl-3-phenylureido)methyl)-N-hydroxybenzamide Parent CAS No.[1403783-31-2] |
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