| 产品名称 | Sodium butyrate - Butanoic acid, sodium salt |
| 产品货号 | Axon 2209 CAS [156-54-7] MF C4H7NaO2MW 110.09 Purity: 98% Soluble in water and DMSO Description Noncompetitive inhibitor of histone deacetylase (HDAC; IC50 value 0.80 mM). Butyrate inhibits most HDACs, except class III HDAC and class II HDAC6 and HDAC10. Among the fatty acids, butyrate is the most effective in inhibiting HDAC activity and arresting cell proliferation, and stimulating or repressing the expression of specific genes. References Certificates Categories Extra info J.R. Davie. Inhibition of histone deacetylase activity by butyrate. J. Nutr. 2003, 133, S2485-S2493. G. Bora-Tatar et al. Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies. Bioorg. Med. Chem. 2009, 17, 5219-5228. K. Steliou et al. Butyrate histone deacetylase inhibitors. Biores. Open Access. 2012, 1, 192-198. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Epigenetics DNA-damage Response EC 3.5.1.98 Stem Cell Differentiator HDAC Noncompetitive inhibitor of multiple histone deacetylases (HDACs) Chemical name sodium butyrate Parent CAS No. [107-92-6] Order Size Unit Price Stock 100 mg €50.00 In Stock |
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| 产品品牌 | axonmedchem |
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Sodium butyrate - Butanoic acid, sodium saltAxon 2209 CAS [156-54-7] MF C4H7NaO2
Description
Noncompetitive inhibitor of histone deacetylase (HDAC; IC50 value 0.80 mM). Butyrate inhibits most HDACs, except class III HDAC and class II HDAC6 and HDAC10. Among the fatty acids, butyrate is the most effective in inhibiting HDAC activity and arresting cell proliferation, and stimulating or repressing the expression of specific genes.
Noncompetitive inhibitor of multiple histone deacetylases (HDACs)
Chemical namesodium butyrate Parent CAS No.[107-92-6] |
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