| 产品名称 | NVP-LDE225 - LDE 225 | Sonidegib | Erismodegib |
| 产品货号 | Axon 1619 CAS [956697-53-3] MF C26H26F3N3O3MW 485.50 Purity: 98% Soluble in DMSO Description Potent, selective and orally bioavailable Smoothened (SMO) antagonist (IC50: 50 nM); it inhibits hedgehog (Hh) signaling pathway via antagonism of the Smoothened receptor (SMO) References Certificates Categories Extra info S Pan et al. Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist. ACS Med. Chem. Lett., 2010, 1 (3), pp 130–134. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology CNS Stem Cell Smoothened (SMO) Hedgehog F Smoothened (SMO) antagonist Chemical name N-(6-((2S,6R)-2,6-dimethylmorpholino)pyridin-3-yl)-2-methyl-4'-(trifluoromethoxy)biphenyl-3-carboxamide Parent CAS No. [956697-53-3] Order Size Unit Price Stock 5 mg €85.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
NVP-LDE225 - LDE 225 | Sonidegib | ErismodegibAxon 1619 CAS [956697-53-3] MF C26H26F3N3O3
Description
Potent, selective and orally bioavailable Smoothened (SMO) antagonist (IC50: 50 nM); it inhibits hedgehog (Hh) signaling pathway via antagonism of the Smoothened receptor (SMO)
Smoothened (SMO) antagonist
Chemical nameN-(6-((2S,6R)-2,6-dimethylmorpholino)pyridin-3-yl)-2-methyl-4'-(trifluoromethoxy)biphenyl-3-carboxamide Parent CAS No.[956697-53-3] |
| 产品资料 |
