| 产品名称 | JZP 361 |
| 产品货号 | Axon 2486 CAS [1680193-80-9] MF C22H20ClN5OMW 405.88 Purity: 99% Soluble in DMSO Description Selective reversible inhibitor of monoacylglycerol lipase (MAGL; IC50 value 46 nM) with 35-fold higher selectivity over human α/β-hydrolase-6 (ABHD6) and 150-fold higher selectivity over human FAAH. The Loratidine analog JZP 361 fully retained H1 antagonistic activity as well (pA2 value 6.81) but is devoid of cannabinoid receptor (CB) affinity. KEYWORDS: JZP 361 | Supplier | MAGL inhibitor - H1 antagonist | JZP361 | CAS [1680193-80-9] | 2-arachidonoyl glycerol (2-AG) | MAGL | Inhibitor | antagonist | monoacylglycerol | lipase | histamine | allergy | Fatty acid amide hydrolase | FAAH | ABHD6 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
JZP 361Axon 2486 CAS [1680193-80-9] MF C22H20ClN5O
DescriptionSelective reversible inhibitor of monoacylglycerol lipase (MAGL; IC50 value 46 nM) with 35-fold higher selectivity over human α/β-hydrolase-6 (ABHD6) and 150-fold higher selectivity over human FAAH. KEYWORDS: JZP 361 | Supplier | MAGL inhibitor - H1 antagonist | JZP361 | CAS [1680193-80-9] | 2-arachidonoyl glycerol (2-AG) | MAGL | Inhibitor | antagonist | monoacylglycerol | lipase | histamine | allergy | Fatty acid amide hydrolase | FAAH | ABHD6
Selective reversible inhibitor of MAGL with Histamine H1 antagonistic activity
Chemical name[4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl]-1H-1,2,4-triazol-1-yl-methanone Parent CAS No.[1680193-80-9] |
| 产品资料 |
