产品名称 NS 3694
产品货号 Axon 1883 CAS [426834-38-0] MF C15H10ClF3N2O3MW 358.70 Purity: 99% Soluble in 0.1N NaOH(aq) and DMSO Description Apoptosis inhibitor; NS3694 inhibits the formation of the apoptosome Apaf-1 by blocking the activation of the initiator caspase 9; NS2694 exhibits no effect on apoptosome-independent caspase activation and enzymatic activity of caspases References Certificates Categories Extra info U Lademann et al. Diarylurea compounds inhibit caspase activation by preventing the formation of the active 700-kilodalton apoptosome complex. Mol. Cell Biol. 2003, 23(21), 7829-7837.   A. Degterev et al. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nature Chem. Biol. 2005, 1, 112.  Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Signaling & Oncology EC 3.4.22.62 Procaspase Inhibitor of apoptosis; Inhibits formation of apoptosome complex Chemical name 4-chloro-2-(3-(3-(trifluoromethyl)phenyl)ureido)benzoic acid Parent CAS No. [426834-38-0] Order Size Unit Price Stock 10 mg €90.00 In Stock
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NS 3694

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1883

CAS [426834-38-0]

MF C15H10ClF3N2O3
MW 358.70

  • Purity: 99%
  • Soluble in 0.1N NaOH(aq) and DMSO

NS 3694

Description

Apoptosis inhibitor; NS3694 inhibits the formation of the apoptosome Apaf-1 by blocking the activation of the initiator caspase 9; NS2694 exhibits no effect on apoptosome-independent caspase activation and enzymatic activity of caspases
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