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产品名称 DY 268
产品货号 Axon 2561 CAS [1609564-75-1] MF C30H32N4O5SMW 560.66 Purity: 100% Soluble in DMSO Description Highly potent FXR antagonist with a promising in vitro profile (IC50 values 7.5 nM and 468.5 nM in FXR binding assay and cell-based FXR antagonistic assay, respectively). DY 268 shows no FXR agonistic activity nor cytotoxicity, making it an excellent chemical tool to elucidate the biological function of FXR. KEYWORDS: DY 268 | supplier | FXR antagonist | DY268 | CAS [1609564-75-1] | Chenodeoxycholic acid | FXR | Antagonist | Nuclear | Farnesoid X Receptor | cholesterol | metabolism
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产品品牌 axonmedchem
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DY 268

Based on 2 publications in PubMed 9 10 2

Axon 2561

CAS [1609564-75-1]

MF C30H32N4O5S
MW 560.66

  • Purity: 100%
  • Soluble in DMSO

DY 268

Description

Highly potent FXR antagonist with a promising in vitro profile (IC50 values 7.5 nM and 468.5 nM in FXR binding assay and cell-based FXR antagonistic assay, respectively). DY 268 shows no FXR agonistic activity nor cytotoxicity, making it an excellent chemical tool to elucidate the biological function of FXR.

KEYWORDS: DY 268 | supplier | FXR antagonist | DY268 | CAS [1609564-75-1] | Chenodeoxycholic acid | FXR | Antagonist | Nuclear | Farnesoid X Receptor | cholesterol | metabolism

Highly potent FXR antagonist with a promising in vitro profile

Chemical name

1-(3-methoxybenzyl)-N-(4-methyl-3-(morpholinosulfonyl)phenyl)-3-p-tolyl-1H-pyrazole-4-carboxamide

Parent CAS No.

[1609564-75-1]
产品资料