产品名称

SP 2509

产品货号

Axon 2864 CAS [1423715-09-6] MF C19H20ClN3O5SMW 437.90 Purity: 98% Soluble in DMSO Description SP 2509 is a potent, reversible, and specific LSD1 inhibitor with an IC50 value of 0.013 µM (Ki value of 31 nM). Moreover, SP 2509 inhibits proliferation and survival in several cancer cell lines, including breast and colorectal cancer. KEYWORDS: SP 2509 | supplier | LSD1 inhibitor | SP2509 | SP-2509 | CAS [1423715-09-6] | CAS [1287421-04-8] | Histone | Histone demethylase | Inhibitor | Enzymes | BHC 110 inhibitor VII | Histone Lysine Demethylase Inhibitor XIV | KIAA 1718 inhibitor VII | LSD 1 inhibitor VII

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

SP 2509

Based on 9 reference(s) in Google Scholar 8 10 9

Axon 2864

CAS [1423715-09-6]

MF C19H20ClN3O5S
MW 437.90

Purity: 98%
Soluble in DMSO

SP 2509

Description

SP 2509 is a potent, reversible, and specific LSD1 inhibitor with an IC50 value of 0.013 µM (Ki value of 31 nM). Moreover, SP 2509 inhibits proliferation and survival in several cancer cell lines, including breast and colorectal cancer.

KEYWORDS: SP 2509 | supplier | LSD1 inhibitor | SP2509 | SP-2509 | CAS [1423715-09-6] | CAS [1287421-04-8] | Histone | Histone demethylase | Inhibitor | Enzymes | BHC 110 inhibitor VII | Histone Lysine Demethylase Inhibitor XIV | KIAA 1718 inhibitor VII | LSD 1 inhibitor VII

V Sorna et al. High-throughput virtual screening identifies novel N'-(1-phenylethylidene)-benzohydrazides as potent, specific, and reversible LSD1 inhibitors. J Med Chem. 2013 Dec 12;56(23):9496-508.

Cell Signaling & Oncology Epigenetics Immunology EC 1.14.11 Histone demethylase

Potent, reversible, and specific LSD1 inhibitor

Chemical name

(E)-N'-(1-(5-Chloro-2-hydroxyphenyl)ethylidene)-3-(morpholinosulfonyl)benzohydrazide

Parent CAS No.

[1423715-09-6]

产品资料