产品名称

NSC 23005 sodium

产品货号

Axon 2695 CAS [1796596-46-7] MF C13H16NNaO4SMW 305.33 Purity: 100% Soluble in water and DMSO Description Novel small molecule inhibitor of INK4C (p18(INK4C) or p18) that promotes expansion of both murine and human HSCs (ED50 value 5.21 nM). This p18SMI shows no significant cytotoxicity toward 32D cells or HSCs, nor does it augment leukemia cell proliferation. KEYWORDS: NSC 23005 sodium | supplier | p18-INK4C inhibitor | NSC23005 sodium | NSC-23005 sodium | CAS [1796596-46-7] | [6314-70-1] | Cyclin Dependent Kinase | INK4 | CDK4 | CDK6 | Regulator Protein | cell cycle | apoptosis | expansion | HSC | Hematopoietic | stem cell | mitotic

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

NSC 23005 sodium

Based on 10 reference(s) in Google Scholar 8 10 10

Axon 2695

CAS [1796596-46-7]

MF C13H16NNaO4S
MW 305.33

Purity: 100%
Soluble in water and DMSO

NSC 23005 sodium

Description

Novel small molecule inhibitor of INK4C (p18(INK4C) or p18) that promotes expansion of both murine and human HSCs (ED50 value 5.21 nM). This p18SMI shows no significant cytotoxicity toward 32D cells or HSCs, nor does it augment leukemia cell proliferation.

KEYWORDS: NSC 23005 sodium | supplier | p18-INK4C inhibitor | NSC23005 sodium | NSC-23005 sodium | CAS [1796596-46-7] | [6314-70-1] | Cyclin Dependent Kinase | INK4 | CDK4 | CDK6 | Regulator Protein | cell cycle | apoptosis | expansion | HSC | Hematopoietic | stem cell | mitotic

XQ Xie et al. Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion. Sci Rep. 2015 Dec 18;5:18115.

Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Stem Cell p53-Tumor Suppression DNA-damage Response INK4

Novel small molecule inhibitor of INK4C (p18(INK4C) or p18)

Chemical name

Sodium 4-(N-cyclohexylsulfamoyl)benzoate

Parent CAS No.

[6314-70-1]

产品资料