产品名称

C 646

产品货号

Axon 1781 CAS [328968-36-1] MF C24H19N3O6MW 445.42 Purity: 99% Moderately soluble in DMSO Description Competitive p300/CBP histone acetyltransferase (HAT) inhibitor with a Ki of 400 nM; Selective versus other acetyltransferases References Certificates Categories Extra info EM Bowers et al. Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor. Chem. Biol. 2010, 17, 471-482. [onlne] NY Crump et al. Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP. Proc Natl Acad Sci U S A. 2011, 108(19), 7814-7819. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Epigenetics HAT EC 2.3.1.48 HAT inhibitor (p300/CBP selective) Chemical name 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl)methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid Parent CAS No. [328968-36-1] Order Size Unit Price Stock 2 mg €60.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

C 646

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1781

CAS [328968-36-1]

MF C24H19N3O6
MW 445.42

Purity: 99%
Moderately soluble in DMSO

C 646

Description

Competitive p300/CBP histone acetyltransferase (HAT) inhibitor with a Ki of 400 nM; Selective versus other acetyltransferases

EM Bowers et al. Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor. Chem. Biol. 2010, 17, 471-482. [onlne]

NY Crump et al. Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP. Proc Natl Acad Sci U S A. 2011, 108(19), 7814-7819.

HAT inhibitor (p300/CBP selective)

Chemical name

4-(4-((5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl)methylene)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid

Parent CAS No.

[328968-36-1]

产品资料