产品名称

Compound 120 - Atazanavir, deuterated | CTP 518

产品货号

Axon 1753 CAS [N.A.] MF C38H37D15N6O7.H2O4SMW 818.03 Purity: 99% Optical purity: Optically pure Soluble in DMSO Description A partially dueterated analog of Atazanavir (Axon 1441), an oral HIV protease inhibitor; A deuterium-containing medicine with improved ADME properties; Compound 120 showed an approximately 50% increase in half life compared with Atazanavir. References Certificates Categories Extra info SL Harbeson et al. Azapeptide derivatives. Patent Concert Pharmaceuticals Inc. WO2008156632 (A1) Certificate of Analysis Material Safety Data Sheet Immunology Non Selective EC 3.4.23.16 Deuterated Protease inhibitor (see Axon 1441) Chemical name (3S,8S,9S,12S)-3-(1,1-dimethylethyl)-12-[1,1-di(methyl-d3)ethyl-2,2,2-d3]-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-2,5,6,10,13-Pentaazatetradecanedioic acid, 1,14-di(methyl-d3) ester sulfate Parent CAS No. [1092540-56-1] Order Size Unit Price Stock 2 mg €115.00 In Stock

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

Compound 120 - Atazanavir, deuterated | CTP 518

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1753

CAS [N.A.]

MF C38H37D15N6O7.H2O4S
MW 818.03

Purity: 99%
Optical purity: Optically pure
Soluble in DMSO

Compound 120

Description

A partially dueterated analog of Atazanavir (Axon 1441), an oral HIV protease inhibitor; A deuterium-containing medicine with improved ADME properties; Compound 120 showed an approximately 50% increase in half life compared with Atazanavir.

SL Harbeson et al. Azapeptide derivatives. Patent Concert Pharmaceuticals Inc. WO2008156632 (A1)

Deuterated Protease inhibitor (see Axon 1441)

Chemical name

(3S,8S,9S,12S)-3-(1,1-dimethylethyl)-12-[1,1-di(methyl-d3)ethyl-2,2,2-d3]-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-2,5,6,10,13-Pentaazatetradecanedioic acid, 1,14-di(methyl-d3) ester sulfate

Parent CAS No.

[1092540-56-1]

产品资料