产品名称

Cardiogenol C hydrochloride

产品货号

Axon 2550 CAS [1049741-55-0] MF C13H16N4O2.HClMW 296.75 Purity: 99% Soluble in water and DMSO Description Selective and efficient inducer of the differentiation of ESCs to cardiomyocytes (EC50 value 0.1 µM for inducing the differentiation of myosin heavy chain (MHC) positive cardiomyocytes from ESCs in P19CL6 cells). Cardiogenol C induces cardiomyogenic function in lineage-committed progenitor cells, and can thus be considered a promising tool to improve cardiac repair by cell therapy. KEYWORDS: Cardiogenol C | supplier | Stem cell differentiator | CAS [671225-39-1] | [1049741-55-0] | Stem cells (iPSC) | Modulator | differentiation | ESCs | cardiomyocytes | myosin heavy chain |MHC| cardiac repair

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

Cardiogenol C hydrochloride

Based on 194 reference(s) in Google Scholar 9 10 194

Axon 2550

CAS [1049741-55-0]

MF C13H16N4O2.HCl
MW 296.75

Purity: 99%
Soluble in water and DMSO

Cardiogenol C hydrochloride

Description

Selective and efficient inducer of the differentiation of ESCs to cardiomyocytes (EC50 value 0.1 µM for inducing the differentiation of myosin heavy chain (MHC) positive cardiomyocytes from ESCs in P19CL6 cells). Cardiogenol C induces cardiomyogenic function in lineage-committed progenitor cells, and can thus be considered a promising tool to improve cardiac repair by cell therapy.

X Wu et al. Small molecules that induce cardiomyogenesis in embryonic stem cells. J Am Chem Soc. 2004 Feb 18;126(6):1590-1.

AK Mike et al. Small molecule cardiogenol C upregulates cardiac markers and induces cardiac functional properties in lineage-committed progenitor cells. Cell Physiol Biochem. 2014;33(1):205-21.

Stem cell differentiator; inducer of the differentiation of ESCs to cardiomyocytes

Chemical name

2-(2-(4-methoxyphenylamino)pyrimidin-4-ylamino)ethanol hydrochloride

Parent CAS No.

[671225-39-1]

产品资料