产品名称 Enzastaurin - LY 317615
产品货号 Axon 1682 CAS [170364-57-5] MF C32H29N5O2MW 515.60 Purity: 99% Soluble in DMSO Description Selective protein kinase C β (PKC-β) inhibitor; Enzastaurin inhibits PKC-β, PKCα, PKCγ and PKCε with IC50 values of 6, 39, 83 and 110 nM, respectively References Certificates Categories Extra info JR Graff et al. The Protein Kinase Cβ–Selective Inhibitor, Enzastaurin (LY317615.HCl), Suppresses Signaling through the AKT Pathway, Induces Apoptosis, and Suppresses Growth of Human Colon Cancer (...). Cancer Res. 2005, 65, 7462-7469.   MA Rizvi et al. Enzastaurin (LY317615), a protein kinase Cβ inhibitor, inhibits the AKT pathway and induces apoptosis in multiple myeloma cell lines. Mol. Cancer Ther. 2006, 5, 1783-1789. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Immunology Pain & Inflammation NF-κB PI3K-Akt-mTOR EC 2.7.11.13 PKC PKC-β inhibitor Chemical name 3-(1-methyl-1H-indol-3-yl)-4-(1-(1-(pyridin-2-ylmethyl)piperidin-4-yl)-1H-indol-3-yl)-1H-pyrrole-2,5-dione Parent CAS No. [170364-57-5] Order Size Unit Price Stock 10 mg €95.00 In Stock
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Enzastaurin - LY 317615

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1682

CAS [170364-57-5]

MF C32H29N5O2
MW 515.60

  • Purity: 99%
  • Soluble in DMSO

Enzastaurin

Description

Selective protein kinase C β (PKC-β) inhibitor; Enzastaurin inhibits PKC-β, PKCα, PKCγ and PKCε with IC50 values of 6, 39, 83 and 110 nM, respectively
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