产品名称

AM 4113

产品货号

Axon 2791 CAS [614726-85-1] MF C17H12Cl3N3OMW 380.66 Purity: 99% Soluble in DMSO Description Cannabinoid CB1 receptor antagonist. AM 4113 was able to bind with high affinity to CB1 receptors, exhibiting 100-fold selectivity for CB1 vs CB2 receptors (Ki values of 0.89 and 92 nM for CB1 and hCB2, respectively). AM 4113 does not show inverse agonist properties (ie no effects on cyclic-AMP production). KEYWORDS: AM 4113 | supplier | CB1 antagonist | AM4113 | AM-4113 | CAS [614726-85-1] | Cannabinoids | CB1 | Antagonist | Receptors

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

AM 4113

Based on 25 reference(s) in Google Scholar 8 10 25

Axon 2791

CAS [614726-85-1]

MF C17H12Cl3N3O
MW 380.66

Purity: 99%
Soluble in DMSO

AM 4113

Description

Cannabinoid CB1 receptor antagonist. AM 4113 was able to bind with high affinity to CB1 receptors, exhibiting 100-fold selectivity for CB1 vs CB2 receptors (Ki values of 0.89 and 92 nM for CB1 and hCB2, respectively). AM 4113 does not show inverse agonist properties (ie no effects on cyclic-AMP production).

KS Sink et al. The novel cannabinoid CB1 receptor neutral antagonist AM4113 suppresses food intake and food-reinforced behavior but does not induce signs of nausea in rats. Neuropsychopharmacology. 2008 Mar;33(4):946-55.

CB1 antagonist

Chemical name

5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide

Parent CAS No.

[614726-85-1]

产品资料