| 产品名称 | LDN 57444 |
| 产品货号 | Axon 2449 CAS [668467-91-2] MF C17H11Cl3N2O3MW 397.64 Purity: 99% Soluble in DMSO Description Reversible, competitive inhibitor of UCH-L1 (Ki value 0.40 µM; IC50 values 0.88 µM and 25 µM for UCH-L1 and UCH-L3 inhibition, respectively), that promotes proliferation of H1299 NSCLC cells and SH-SY5Y neuroblastoma cells. A usefull tool to study the role of UCH-L1 in Parkinson’s disease, cancer, and neuropathic pain. References Certificates Categories Extra info Y. Liu et al. Discovery of inhibitors that elucidate the role of UCH-L1 activity in the H1299 lung cancer cell line. Chem Biol. 2003 Sep;10(9):837-46. UCH-L1 inhibition involved in CREB dephosphorylation in hippocampal slices. M Xie et al. J Mol Neurosci. 2014 May;53(1):59-68. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology CNS Pain & Inflammation Ubiquitin EC 3.4.19.12 Deubiquitinase Reversible, competitive inhibitor of UCH-L1 deubiquitinase Chemical name 3-(acetoxyimino)-5-chloro-1-(2,5-dichlorobenzyl)indolin-2-one Parent CAS No. [668467-91-2] Order Size Unit Price Stock 10 mg €95.00 In Stock |
| 产品价格 | 现货询价，电话：010-67529703 |
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| 产品品牌 | axonmedchem |
| 产品概述 | |
| 产品详情 |
LDN 57444Axon 2449 CAS [668467-91-2] MF C17H11Cl3N2O3
Description
Reversible, competitive inhibitor of UCH-L1 (Ki value 0.40 µM; IC50 values 0.88 µM and 25 µM for UCH-L1 and UCH-L3 inhibition, respectively), that promotes proliferation of H1299 NSCLC cells and SH-SY5Y neuroblastoma cells. A usefull tool to study the role of UCH-L1 in Parkinson’s disease, cancer, and neuropathic pain.
Reversible, competitive inhibitor of UCH-L1 deubiquitinase
Chemical name3-(acetoxyimino)-5-chloro-1-(2,5-dichlorobenzyl)indolin-2-one Parent CAS No.[668467-91-2] |
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