产品名称

A 381393

产品货号

Axon 2944 CAS [726174-00-1] MF C20H24N4MW 320.43 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Recently added

产品价格

现货询价，电话：010-67529703

产品规格

产品品牌

axonmedchem

产品概述

产品详情

A 381393

Based on 4 reference(s) in Google Scholar 8 10 4

Axon 2944

CAS [726174-00-1]

MF C20H24N4
MW 320.43

Purity: 99%
Soluble in 0.1N HCl(aq) and DMSO

Recently added

A 381393

Description

Potent, brain-penetrant, selective antagonist of the dopamine D4 receptor with both in vitro and in vivo activity (Ki value of 1.5 nM). A 381393 lacks any significant intrinsic agonist activity.

M Nakane et al. 2-[4-(3,4-Dimethylphenyl)piperazin-1-ylmethyl]-1H benzoimidazole (A-381393), a selective dopamine D4 receptor antagonist. Neuropharmacology. 2005 Jul;49(1):112-21.

CNS D4 A17

Potent, brain-penetrant, selective antagonist of the dopamine D4 receptor

Chemical name

2-((4-(3,4-Dimethylphenyl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole

Parent CAS No.

[726174-00-1]

产品资料