产品名称 IITZ-01
产品货号 Axon 2933 CAS [1807988-47-1] MF C26H23FN8OMW 482.51 Purity: 99% Soluble in DMSO Recently added
产品价格 现货询价,电话:010-67529703
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产品品牌 axonmedchem
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IITZ-01

Based on 2 reference(s) in Google Scholar 8 10 2

Axon 2933

CAS [1807988-47-1]

MF C26H23FN8O
MW 482.51

  • Purity: 99%
  • Soluble in DMSO
Recently added

IITZ-01

Description

IITZ-01 is a potent lysosomotropic autophagy inhibitor which has single-agent antitumor efficacy in triple-negative breast cancer in vitro and in vivo. Screening against the growth of cancer cell lines MCF-7, MDAMB-231, PC-3, DU-145, HT-29 and HGC-27 gave IC50 values of 1.0 µM, 1.5 µM, 0.8 µM, 1.0 µM, 1.1 µM, 0.8 µM, respectively.

KEYWORDS: IITZ-01 | supplier | Autophagy inhibitor | IITZ 01 | IITZ01 | CAS [1807988-47-1] | Cellular Metabolic Homeostasis | Lysosomotropic | Inhibitor | Apoptosis | Malaria | Triple-negative breast cancer | TNBC

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