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| Product Name | AR, Recombinant, Human, aa551-919, His-SUMO-Tag (Androgen Receptor) |
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| Description | Purity ~90% (SDS-PAGE). Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3. Isoform 3 and isoform 4 lack the C-terminal ligand-binding domain and may therefore constitutively activate the transcription of a specific set of genes independently of steroid hormones. Source: Recombinant protein corresponding to aa551-919 from human AR, fused to His-Tag at N-terminal and Myc-Tag at C-terminal expressed in E. coli. Molecular Weight: ~62.4kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4 |
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| Gene, Accession, CAS # | SwissProt: P10275 |
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| Catalog # | 372312 |
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| Order / More Info | AR, Recombinant, Human, aa551-919, His-SUMO-Tag (Androgen Receptor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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