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| Antigenic Specificity | CD46 Sushi domains 1 and 2 |
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| Clone | 2C8 |
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| Host Species | Human |
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| Reactive Species | cross-reacted with cynomologous monkey |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | For in vitro and in vivo research use. Not intended for any applications in human. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Anti-Human CD46 Therapeutic Antibody Fab Fragment (2C8). By two rounds selection, the anti-CD46 antibodie specifically bind to both live tumor cells and the recombinant human CD46-Fc fusion protein. The human anti-CD46 antibodies can internalize and enter tumor cells via the macropinocytosis pathway, and these antibodies as well as the antibody-drug conjugates can be used for the diagnosis and therapeutic targeting of CD46-over expressing tumors. |
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| Immunogen | Selection (recombinant CD46-Fc fusion protein) |
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| Other Names | CD46; CD46 molecule, complement regulatory protein; MCP; TLX; AHUS2; MIC10; TRA2.10; membrane cofactor protein; measles virus receptor; complement membrane cofactor protein; trophoblast leucocyte common antigen; trophoblast leukocyte common antigen; CD46 antigen, complement regulatory protein; trophoblast-lymphocyte cross-reactive antigen; antigen identified by monoclonal antibody TRA-2-10; membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen) |
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| Gene, Accession # | Gene ID: 4179 |
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| Catalog # | TAB-0296CL-F(E) |
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| Price | |
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| Order / More Info | CD46 Sushi domains 1 and 2 Antibody from CREATIVE BIOLABS |
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| Product Specific References | n/a |
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