产品详情 |
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Antigenic Specificity | Epithelial Splicing Regulatory Protein 1 (ESRP1) |
Clone | 27H12-F3-H5 |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG2b kappa |
Format | purified |
Size | 25 µL |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Epithelial splicing regulatory protein 1 (Esrp-1) is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2, and also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Esrp-1 acts by directly binding specific sequences in mRNAs. It binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.Synonyms: Rbm35a, Epithelial splicing regulatory protein 1, RNA-binding protein 35A, RNA-binding motif protein 35A. |
Immunogen | Anti-Esrp-1 was produced by repeated immunizations of full length recombinant mouse Esrp-1 fusion protein.Immunogen Type: RecombinantProtein |
Other Names | rbm35a|RBM35A|RMB35A|2210008M09Rik|A630065D16|BC031468|Rbm35a|RGD1560481|wu:fi28a07|zgc:154050 |
Gene, Accession # | Gene ID: 207920 |
Catalog # | ABIN964640 |
Price | |
Order / More Info | Epithelial Splicing Regulatory Protein 1 (ESRP1) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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