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Product Name | MeOSuc-Ala-Ala-Pro-Val-AMC |
Description | Purity >98%. MeOSuc-Ala-Ala-Pro-Val-AMC (MeOSuc-AAPV-AMC) is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase. The methoxy succinyl (MeO-Suc) peptide AAPV is avidly hydrolyzed by these elastases but not by cathepsin G. The addition of 7-amino-4-methylcoumarin (AMC) generates a peptide of low fluorescence (excitation: 355-380 nm; emission 440-460 nm) that demonstrates a linear increase in fluorescence in the presence of elastase. This peptidyl-AMC substrate detects as little as 11 pM human leukocyte elastase and 18 pM porcine pancreatic elastase. |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Other Names | N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-valinamide, I 1270, MeOSuc-AAPV-AMC, Methoxy Succinyl-Ala-Ala-Pro-Val-AMC |
Gene, Accession, CAS # | CAS: 72252-90-5 |
Catalog # | LS-H8636 |
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Order / More Info | MeOSuc-Ala-Ala-Pro-Val-AMC from LIFESPAN BIOSCIENCES INC. |
Product Specific References | n/a |
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