| 产品详情 |
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| Product Name | Recombinant Human Ubiquitin carboxyl-terminal hydrolase 14 (USP14) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 60.1kDa. Full Length: 1-494aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chokine receptor CXCR4 which is critical for CXCL12-induced cell chotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs). |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Deubiquitinating enzyme 14Ubiquitin thioesterase 14Ubiquitin-specific-processing protease 14 |
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| Gene, Accession, CAS # | USP14, UniProt: P54578 |
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| Catalog # | RPC22212 |
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| Price | |
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| Order / More Info | Recombinant Human Ubiquitin carboxyl-terminal hydrolase 14 (USP14) from BIOMATIK |
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| Product Specific References | n/a |
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