产品详情 |
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Antigenic Specificity | Lrp5 |
Clone | CBYJL-2408 |
Host Species | Recombinant Rat |
Reactive Species | mouse |
Isotype | IgG2b, κ |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | FC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rat Anti-Lrp5 Recombinant Antibody (CBYJL-2408). Provided herein is a Rat monoclonal antibody, which binds to Low Density Lipoprotein Receptor-Related Protein 5 (Lrp5). The antibody can be used for immunoassay techniques, such as FC. Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a essential role in bone formation. Plays a role in norrin (NDP) signal transduction. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signal |
Immunogen | n/a |
Other Names | HBM; LR3; LRP7; OPPG; BMND1; mKIAA4142; low-density lipoprotein receptor-related protein 5; LRP-5; LRP-7; low-density lipoprotein receptor-related protein 7 |
Gene, Accession # | Gene ID: 16973, UniProt: O75197 |
Catalog # | CBMAB-L2730-YJ |
Price | |
Order / More Info | Lrp5 Antibody from CREATIVE BIOLABS |
Product Specific References | n/a |
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