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Antigenic Specificity | Lactalbumin, alpha- (LALBA) (aa 20-37), (N-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | LALBA(lactalbumin, alpha or alpha-lactalbumin) is a protein that in humans is encoded by the LALBA gene. The LALBA gene is mapped on 12q13.11. alpha-Lactalbumin is an important whey protein in cow's milk(1 g/l), and is also present in the milk of many other mammalian species. In primates, alpha-lactalbumin expression is upregulated in response to the hormone prolactin and increases the production of lactose. alpha-Lactalbumin forms the regulatory subunit of the lactose synthase(LS) heterodimer and beta-1, 4-galactosyltransferase(beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transferring galactose moieties to glucose. As a multimer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of human alpha-lactalbumin that may form in acidic environments such as the stomach, called HAMLET, probably induces apoptosis in tumor and immature cells. |
Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human alpha Lactalbumin(20-37aa KQFTKCELSQLLKDIDGY). |
Other Names | LALBA|AW208827|a-LACTA|alfaLA |
Gene, Accession # | Gene ID: 3906 |
Catalog # | ABIN1673187 |
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Order / More Info | Lactalbumin, alpha- (LALBA) (aa 20-37), (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 3059144, 3479943, 7644538 |
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