| 产品详情 |
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| Product Name | Gedunin |
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| Description | A natural inhibitor of p23 chaperone function; inhibits Hsp90 expression in vitro in NTERA-2 cells at 5 µg/ml; binds to and blocks p23 to induce apoptosis in HeLa-PRB cells (20 µM); inhibits breast cancer cell proliferation in vitro (IC50s = 8.84 and 3.22 µM in MCF-7 and SKBr-3 cells, respectively); inhibits PANC-1 pancreatic cancer cell growth in vitro (IC50 = 25 µM); has anti-inflammatory effects in mouse models of articular inflammation when used at doses of 0.05-0.5 mg/kg and allergic inflammation when used at a dose of 0.5 mg/kg; targets LPS binding and TLR4 signaling in macrophages when used at a concentration of 10 µM |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NSC 113497 |
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| Gene, Accession, CAS # | CAS: 2753-30-2 |
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| Catalog # | 17328-1 |
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| Price | |
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| Order / More Info | Gedunin from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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