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| Product Name | RASSF5, Recombinant, Human, aa1-265, GST-Tag (Ras Association Domain-containing Protein 5) |
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| Description | Purity ~90% (SDS-PAGE). Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis. Source: Recombinant protein corresponding to aa1-265 from human RASSF5, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~57.4kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | New ras effector 1 Regulator for cell adhesion and polarization enriched in lymphoid tissues |
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| Gene, Accession, CAS # | SwissProt: Q8WWW0 |
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| Catalog # | 374993 |
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| Order / More Info | RASSF5, Recombinant, Human, aa1-265, GST-Tag (Ras Association Domain-containing Protein 5) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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