| 产品详情 |
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| Antigenic Specificity | CD38 |
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| Clone | NIMR-5 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 0.5 mg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FACS),Immunoprecipitation (IP),Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells, and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCR+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B- and T-cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis. |
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| Immunogen | n/a |
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| Other Names | Cd38-rs1|T10 |
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| Gene, Accession # | Gene ID: 12494 |
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| Catalog # | ABIN135201 |
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| Price | |
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| Order / More Info | CD38 Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 8376770, 7869031, 8397252 |
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