产品名称 CD38 Antibody from ANTIBODIES-ONLINE GmbH
产品货号 ABIN135201
产品价格 现货询价,电话:010-67529703
产品规格 0.5 mg
产品品牌 ANTIBODIES-ONLINE GmbH
产品概述
产品详情
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Antigenic SpecificityCD38
CloneNIMR-5
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2a
Formatpurified
Size0.5 mg
Concentrationn/a
ApplicationsFlow Cytometry (FACS),Immunoprecipitation (IP),Immunohistochemistry (IHC)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionMurine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells, and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCR+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B- and T-cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.
Immunogenn/a
Other NamesCd38-rs1|T10
Gene, Accession #Gene ID: 12494
Catalog #ABIN135201
Price
Order / More InfoCD38 Antibody from ANTIBODIES-ONLINE GmbH
Product Specific ReferencesPubMed: 8376770, 7869031, 8397252
产品资料