产品详情 |
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Antigenic Specificity | CD38 |
Clone | HIT2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. Another role of CD38 is provided by enzymatic activity of its extracellular part. CD38 acts as NAD+ glycohydrolase converting NAD+ into ADP-ribose, as ADP-ribosyl cyclase producing cADPR and as cADPR hydrolase, thus affecting levels of calcium-mobilizing metabolites. ADPR produced by CD38 serves as an important second messenger of neutrophil and dendritic cell migration. |
Immunogen | Human thymocytes in foetus |
Other Names | Cd38-rs1|T10 |
Gene, Accession # | Gene ID: 952 |
Catalog # | ABIN125718 |
Price | |
Order / More Info | CD38 Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 18025229, 16720618, 11513738, 25578543, 17132718, 19685493 |
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