| 产品详情 |
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| Antigenic Specificity | C-Fos (aa 250-300) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | rat, human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 40 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Transcription factor C-Fos is one member of Fos family of nuclear oncogenes which includes c-Fos, FosB, Fos-related antigen 1 (FRA1) and Fos-related antigen 2 (FRA2).C-Fos is a major component of the activator protein-1 (AP-1) transcription factor complex and dimerizes with Jun proteins (c-Jun, JunB and JunD) to form AP-1 complex. AP-1 upregulates transcription of a diverse range of genes containing AP-1 regulatory elements. And phosphorylation of c-Fos on serine 32 and threonine 232 by ERK-5 increases protein stability and nuclear localization. C-Fos probably serves as a genetic regulator for cellular mechanisms mediating neuronal excitability and survival vial regulation of kainic acid receptor GLUR6 and expression of brain-derived neurotrophic factor BDNF.Rabbit Anti-C-Fos Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 250~300 of human C-Fos (Swiss Prot: P01100). |
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| Immunogen | KLH-coupled synthetic peptide within AA 250~300 of human C-Fos . |
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| Other Names | AP-1|C-FOS|p55|c-fos|D12Rfj1|cFos|cFOS|fos |
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| Gene, Accession # | Gene ID: 2353,314322 |
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| Catalog # | ABIN1574157 |
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| Price | |
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| Order / More Info | C-Fos (aa 250-300) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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