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| Product Name | Recombinant Human Ras GTPase-activating protein SynGAP (SYNGAP1), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 25.5kDa. Partial: 1161-1343aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Neuronal RasGAP (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1) (KIAA1938) |
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| Gene, Accession, CAS # | SYNGAP1, UniProt: Q96PV0 |
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| Catalog # | RPC25777 |
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| Price | |
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| Order / More Info | Recombinant Human Ras GTPase-activating protein SynGAP (SYNGAP1), partial from BIOMATIK |
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| Product Specific References | n/a |
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