| 产品详情 |
| Edit |   |
|---|
| Product Name | OF-1 |
|---|
| Description | MW: 440.31. Purity ≥98% by HPLC. OF-1 is a selective BRPF1B and BRPF2 bromodomain inhibitor (Kd values are 100 and 500 nM respectively). OF-1 displays 39-fold selectivity for BRPF1B and BRPF2 over BRD4. It increases thermal stability of full length BRPF1B at 1 uM; in the cellular thermal shift assay. It also demonstrates accelerated fluorescence recovery after photobleaching (FRAP) at 5 uM in the BRPF2 FRAP assay. OF-1 displays modest general cytotoxicity. |
|---|
| Size | 5 mg, 25 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | [4-Bromo-N- (2; 3-dihydro-6-methoxy-1; 3-dimethyl-2-oxo-1H-benzimidazol-5-yl)-2-methylbenzenesulfonamide] |
|---|
| Gene, Accession, CAS # | CAS: 919973-83-4 |
|---|
| Catalog # | MBS845772 |
|---|
| Price | |
|---|
| Order / More Info | OF-1 from MYBIOSOURCE INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|