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Antigenic Specificity | Caspase-10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Alexa Fluor® 488 conjugate |
Size | 100ul |
Concentration | 1ug/ul |
Applications | IF(IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Caspase-10 Polyclonal Antibody, Alexa Fluor® 488 Conjugated. • Target Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. Isoform C is proteolytically inactive. |
Immunogen | KLH conjugated synthetic peptide derived from human Caspase-10. Immunogen Range: 480-521/521 |
Other Names | MCH4; ALPS2; FLICE2; Caspase-10; CASP-10; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; ICE-like apoptotic protease 4; CASP10 |
Gene, Accession # | Gene ID: 843, SwissProt: Q92851 |
Catalog # | bs-0092R-A488 |
Price | |
Order / More Info | Caspase-10 Antibody from BIOSS ANTIBODIES |
Product Specific References | n/a |