| 产品详情 |
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| Product Name | (-)-Chaetominine |
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| Description | A cytotoxic alkaloid; inhibits the growth of K562 leukemia and SW1116 colon cancer cells (IC50s = 20 and 28 nM, respectively); induces apoptosis of K562 cells via upregulation of the Bax/Bcl-2 ratio, decreasing mitochondrial membrane potential, inducing cytochrome C release, and activation of caspase-3 and caspase-9; decreases MRP1-mediated doxorubicin efflux and restores sensitivity to doxorubicin in resistant K562 cells |
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| Size | 2.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SW-1116 k-562 Aspergillus BCL2 |
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| Gene, Accession, CAS # | CAS: 918659-56-0 |
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| Catalog # | 13135-25 |
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| Price | |
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| Order / More Info | (-)-Chaetominine from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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