| 产品名称 |
EPHB1, Recombinant, Mouse, GST-Tag (Elk, Net, Cek6, Elkh, Hek6, EPHT2, AW488255) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | EPHB1, Recombinant, Mouse, GST-Tag (Elk, Net, Cek6, Elkh, Hek6, EPHT2, AW488255) |
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| Description | Purified (~70-90%). EPHB1 is a member of the Eph family of receptor tyrosine kinases. Ligand-activated EPHB1 forms a signaling complex with Nck, paxillin, and focal adhesion kinase and induces tyrosine phosphorylation of paxillin in a c-Src-dependent manner to promote cell migration. In addition, activated EPHB1 recruits the adaptor proteins Grb2 and p52Shc and promotes p52Shc and c-Src tyrosine phosphorylation as well as MAPK/extracellular signal-regulated kinase (ERK) activation. Expression of dominant-negative c-Src significantly reduced EPHB1-dependent ERK1/2 activation and chemotaxis. Source: Recombinant protein corresponding to mouse EPHB1, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~62kD Specific Activity: 143nmol/min/mg as per activity assay protocol. |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_173447 |
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| Catalog # | 499964 |
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| Price | |
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| Order / More Info | EPHB1, Recombinant, Mouse, GST-Tag (Elk, Net, Cek6, Elkh, Hek6, EPHT2, AW488255) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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