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Product Name | EPCAM, BioAssay™ ELISA Kit (Human) (Epithelial Cell Adhesion Molecule) |
Description | Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell-cell adhesion in epithelia. Also it is involved in cell signaling, migration, proliferation, and differentiation. Additionally, EpCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A & E. Since it is expressed exclusively in epithelia and epithelial-derived neoplasms, EpCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies. Sample Type: Cell culture supernates, serum and plasma (heparin, EDTA) Intended Use: For quantitative detection of human EPCAM in cell culture supernates, serum and plasma (heparin, EDTA). Sensitivity: <10pg/ml Range: 93.7-6000pg/ml Specificity: Natural and recombinant human EPCAM Test Principle: This human EPCAM BioAssay™ ELISA Kit |
Size | 96 tests |
Concentration | n/a |
Applications | ELISA |
Other Names | n/a |
Gene, Accession, CAS # | Gene ID: 4072, SwissProt: P16422 |
Catalog # | 352841 |
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Order / More Info | EPCAM, BioAssay™ ELISA Kit (Human) (Epithelial Cell Adhesion Molecule) from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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