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Product Name | Interleukin 10, Human, Low Range (IL-10, Cytokine Synthesis Inhibitory Factor, CSIF) BioAssay™ ELISA Kit |
Description | Interleukin 10 (IL-10), initially designated cytokine synthesis inhibitory factor (CSIF), was originally identified as a product of murine TH2 clones that suppressed the production of cytokines by TH1 clones responding to stimulation by antigen in the presence of monocyte/macrophage antigen-presenting cells. The human homolog of murine IL-10 was subsequently cloned by cross-hybridization. Human and murine IL-10 are 81% and 73% identical at the nucleotide and amino acid levels, respectively. Both mouse and human IL-10 are also highly homologous to a previously uncharacterized open reading frame in the Epstein-Barr virus (EBV) genome, BCRF1. The BCRF1 gene product is now designated viral IL-10. In mouse, IL-10 is produced by TH2 cells, activated fetal thymocytes, macrophages, keratinocytes, and LY-1+ (CD5+) and normal B cells. Cell lines found to have the capacity to produce IL-10 in humans include: TH0, TH1, and TH2-like CD4+ T cell clones; B cell lines derived from patients with AIDS a |
Size | 96 tests |
Concentration | n/a |
Applications | ELISA |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | I8432-05 |
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Order / More Info | Interleukin 10, Human, Low Range (IL-10, Cytokine Synthesis Inhibitory Factor, CSIF) BioAssay™ ELISA Kit from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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