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Product Name | Recombinant Mouse CD63 antigen (Cd63), partial |
Description | Purity > 90% as determined by SDS-PAGE. MW: 38.5kDa. Extracellular Domain: 103-203aa. N-terminal GST-tagged. Mus musculus (Mouse). Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | CD63 |
Gene, Accession, CAS # | Cd63, UniProt: P41731 |
Catalog # | RPC20019 |
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Order / More Info | Recombinant Mouse CD63 antigen (Cd63), partial from BIOMATIK |
Product Specific References | n/a |
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