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| Product Name | threo Ifenprodil hemitartrate |
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| Description | Potent σ receptor agonist (Ki values are 59.1 and 2 nM for σ1 and σ2 receptors respectively) and GluN2B (formally NR2B) subunit-selective NMDA receptor antagonist (IC50 values are 0.22 and 324.8 μM at GluN2B and GluN2A respectively). Displays ~8-fold reduced affinity at α-adrenoceptors compared to Ifenprodil (Cat.No. 0545). Inhibits the hERG potassium channel (IC50 = 88 nM) and exhibits antiarrhythmic activity in vivo. Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions. MW (observed): 400.49. |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (1S*,2S*)-threo-2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol hemitartrate |
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| Gene, Accession, CAS # | CAS: 1312991-83-5 |
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| Catalog # | 2892/50 |
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| Order / More Info | threo Ifenprodil hemitartrate from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 25490055 |
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