产品详情 |
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Product Name | Thiamet G |
Description | Potent, selective inhibitor of O-GlcNAcase (Ki = 21 nM for human O-GlcNAcase). Decreases the phosphorylation of tau protein in vivo. Promotes autophagy independently of mTOR pathway and reduces toxic protein species in mouse tauopathy model. Orally bioavailable and blood brain barrier permeable. MW (observed): 248.3. |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (3aR,5R,6S,7R,7aR)-2-(Ethylamino)-3a,6,7,7a-tetrahydro-5-(hydroxymethyl)-5H-pyrano[3,2-d]thiazole-6,7-diol |
Gene, Accession, CAS # | CAS: 1009816-48-1 |
Catalog # | 4390/10 |
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Order / More Info | Thiamet G from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 23625921, 23859804 |
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