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Product Name | Frizzled Family Receptor 7 (FZD7) (AA 33-185) protein (His tag) |
Description | Frizzled-7 is a member of the Frizzled family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, it leads to the activation of disheveled proteins, nuclear accumulation of beta-catenin, inhibition of GSK-3 kinase and activation of Wnt target genes. Frizzled-7 is an unconventional G-protein-coupled glycoprotein receptors for Wnt proteins. Frizzled-7 contains a divergent N-terminal signal peptide, a conserved cysteine-rich domain, a variable-length linker region, a seven-pass transmembrane region, and a variable-length C-terminal cytoplasmic domain. Frizzled-7 is expressed in skeletal muscle to mediate muscle regeneration in response to Wnt-7a. It also expressed in embryonic stem cells, contributing to self-renewal signaling.Alternative Names: Frizzled-7, Fz-7, hFz7, FzE3, FZD7 |
Size | 500 µg |
Concentration | n/a |
Applications | n/a |
Other Names | Fz-7|Xfz7|frizzled-7|frizzled7|frz-7|frz7|fz7|fze3|FzE3|fzd7-a|fzd7-b|cFz-7|Fz7 |
Gene, Accession, CAS # | Gene ID: 8324 |
Catalog # | ABIN1691135 |
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Order / More Info | Frizzled Family Receptor 7 (FZD7) (AA 33-185) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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