产品详情 |
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Product Name | Apoptosis activator 2 |
Description | Apoptosis activator 2 is a cell-permeable apoptosis activator that promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. Increases procaspase-9 processing and subsequent caspase-3 activation. Induces apoptosis in tumor cells (IC50 = 4 - 9 µM for leukemia cells) with weak or no effect on normal cell lines or those defective/deficient in Apaf-1, caspase-9 or caspase-3 activity (IC50 > 40 µM). MW: 306.14. Purity ≥98% by HPLC |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1-[(3,4-dichlorophenyl)methyl]indole-2,3-dione |
Gene, Accession, CAS # | CAS: 79183-19-0 |
Catalog # | 2784-5 |
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Order / More Info | Apoptosis activator 2 from BIOVISION, INC. |
Product Specific References | n/a |
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