产品详情 |
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Antigenic Specificity | Neurotrophin 4 (NTF4) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat, human |
Isotype | n/a |
Format | affinity purified |
Size | 200 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NT-4 is a member of the structurally related neurotrophin family of proteins, which includes beta-NGF, BDNF and NT-3. NT-4 is expressed in a number of cell types and tissues, including neuronal cells, normal breast epithelial cells, melanocytes, activated T cells, and granulocytes. NT-4 is required for the development of peripheral sensory neurons. NT-4 may be important for the development of long term memory. Increased NT-4 expression in melanoma cells promotes cell proliferation and migration. NT-4 is secreted from cells as a precursor protein, which is proteolytically cleaved into the mature form. NT-4 signaling is mediated through two distinct receptors, the neurotrophin receptor p75NTR and the Trk tyrosine kinase receptor TrkB. While all neurotrophins bind to the p75NTR receptor, NT-4 preferentially binds to the TrkB receptor.Synonyms: NTF4, NT-4/5, NT4, NT5, NTF5 |
Immunogen | Recombinant protein of human NTF4 |
Other Names | NTF5|GLC10|GLC1O|NT-4|NT-4/5|NT-5|NT4|NT5|NT4P|Ntf5|2900040K06Rik|AI462899|NT4/5|Ntf-5|Ntf4 |
Gene, Accession # | Gene ID: 4909,78405,25730 |
Catalog # | ABIN1514432 |
Price | |
Order / More Info | Neurotrophin 4 (NTF4) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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