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| Product Name | Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7) protein |
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| Description | Matrix metalloproteinase-7 (MMP-7) also known as matrilysin and PUMP (EC 3.4.24.23) cleaves a number of substrates including collagen types IV and X, elastin, fibronectin, gelatin, laminin and proteoglycans. MMP-7 is closely related to the stromelysin family members but is encoded by a different gene. MMP-7 is the smallest of all the MMPs consisting of a pro-peptide domain and a catalytic domain. It lacks the hemopexin-like domain common to other members of the MMPs. MMP-7 is secreted as a 28 kDa proenzyme and can be activated in vitro by organomercurials and trypsin and in vivo by MMP-3 to a 18 kDa active MMP-7 enzyme. Once activated, MMP-7 can activate pro-MMP-1 and pro-MMP-9 but not pro-MMP-2. MMP-7 is widely expressed having been reported in elevated levels in cycling endometrium as well as in colorectal cancers and adenomas, hepatocellular carcinomas, rectal carcinomas, and approximately 50 % of gliomas Synonyms: Matrilysin, EC 3.4.24.23, Pump-1 protease, Uterine metalloproteinase, Matrix metalloproteinase-7, MMP-7, Matrin, MPSL1, PUMP-1, MMP7 |
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| Size | 5 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MAT|MPMM|MMP-7|MPSL1|PUMP-1|matrilysin|LOC727698|MMP7|Matrilysin |
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| Gene, Accession, CAS # | Gene ID: 4316 |
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| Catalog # | ABIN805424 |
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| Order / More Info | Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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