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| Product Name | Insulin-Like Growth Factor 1 (IGF1) (AA 49-118) (Active) protein |
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| Description | Insulin-like Growth Factor I (IGF-I) is a single chain 7 kDa growth-promoting polypeptide originally identified as somatomedin-c. It belongs to the IGF family of peptides, which also includes IGF-II and insulin. The gene expression of IGF-I is mainly regulated by Growth Hormone, and IGF-I executes its functions via signaling through transmembrane tyrosine receptors(IGF Receptors). Most circulating IFG-I is associated with the IGF Binding Protein 3 (IGFBP-3), and the IGFBPs may inhibit the actions of IGFs by competing against the IGF Receptors. IGF-I is active in post-natal and adult animals, and is crucial for somatic growth, as IGF-I null mice show marked retardation in utero. IGF-I is involved in the carcinogenesis, and related to the prostate cancer as well. Recombinant rat Insulin-like Growth Factor I (rrIGF-I) produced in E. coli is a single non-glycosylated polypeptide chain containing 71 amino acids. A fully biologically active molecule, rrIGF-I has a molecular mass of 7.8 kDa analyzed by reducing SDS-PAGE. Synonyms: Somatomedin C, IGF-I, IGFIA, IGF1 |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IGF-1|IGF-1L|IGF-1a|IGF-I|C730016P09Rik|Igf-1|Igf-I|IGF1A|IGFI|IGFIA|Npt2B|IGF-IB|IGF1 |
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| Gene, Accession, CAS # | Gene ID: 24482 |
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| Catalog # | ABIN2017987 |
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| Order / More Info | Insulin-Like Growth Factor 1 (IGF1) (AA 49-118) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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