| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Esrp-1/2 |
|---|
| Clone | 23A7-C9 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG2b kappa |
|---|
| Format | purified |
|---|
| Size | 25 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blotting (WB) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Epithelial splicing regulatory protein 1 (Esrp-1) and Esrp-2 are mRNA splicing factors that regulate the formation of epithelial cell-specific isoforms. They specifically regulate the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2, and also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Esrp-1 and -2 act by directly binding specific sequences in mRNAs. They bind the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. |
|---|
| Immunogen | Anti-Esrp-1/2 was produced by repeated immunizations of full length recombinant mouse Esrp-1 fusion protein.Immunogen Type: RecombinantProtein |
|---|
| Other Names | Rbm35a, Epithelial splicing regulatory protein 1, RNA-binding protein 35A, RNA-binding motif protein 35A, RNA-binding protein 35B, RNA-binding motif protein 35B. |
|---|
| Gene, Accession # | n/a |
|---|
| Catalog # | ABIN964642 |
|---|
| Price | |
|---|
| Order / More Info | Esrp-1/2 Antibody from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|